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. 2024 Dec 10;22(4):15593258241308051. doi: 10.1177/15593258241308051

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© The Author(s) 2024

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Metformin mitigated radiation-induced lung fibrosis. (A)-(C) Representative images (40×) of immunohistochemical staining of Collagen-I, Samd2, and TGF-β1 and the percentages of their positive cells, black arrow: Collagen-I, Samd2, and TGF-β1 posotive cells. (D) Representative images of western blot of Collagen-I, Samd2, and TGF-β1 and their quantified calculation of protein expression. The results are presented as mean ± SD. ^aP < 0.05 vs Control group, ^bP < 0.01 vs Control group, ^cP < 0.05 vs IR group, ^dP < 0.01 vs IR group, ^eP < 0.05 vs L-Met group, ^fP < 0.01 vs L-Met group.