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. 2024 Dec 10;22(4):15593258241308051. doi: 10.1177/15593258241308051

Figure 4.

Figure 4.

Metformin suppressed radiation-induced inflammation response in lung tissue, bronchoalveolar lavage fluid (BALF) , and serum. (A) The production of cytokines high-mobility group box 1 (HMGB1), interleukin-1 beta (IL-β1), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α) in the lung tissue. (B) Cytokines levels in bronchoalveolar lavage fluid (BALF). (C) Cytokines levels in serum. The results are presented as mean ± SD. aP < 0.05 vs Control group, bP < 0.01 vs Control group, cP < 0.05 vs IR group, dP < 0.01 vs IR group, eP < 0.05 vs L-Met group.