TABLE 2.

Thermodynamic parameters of S. pneumoniae GAPN binding from ITC.

	K D	ΔH	ΔS
G3P	53 ± 36 nM	−6.8 ± 0.6 kcal	10.8 ± 3.5 kcal
NADP+	51 ± 32 μM	−2.3 ± 0.8 kcal	12.5 ± 2.8 kcal