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. 2024 Dec 10;39(1):2427175. doi: 10.1080/14756366.2024.2427175

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 2. — CS inhibitors reported by Thomas¹² and Rodrigues-Vendramini¹³.Top panel: initial hit (left) and the improved inhibitor (right) reported by Thomas and colleagues¹². Bottom panel: inhibitors found by virtual screening by Rodrigues-Vendramini and collegues¹³. IC₅₀ values for compounds BF1, BF2, CP1 and CaCS02 were 8, 0.22, 47 and 29 µM, respectively.