FIGURE 1.

MIC distribution for a hypothetical bacterial species targeted in antimicrobial resistance surveillance programs. Arrows indicate the epidemiological cutoff value (ECOFF) established according to EUCAST recommendations, separating the wild type (no resistance determinants) from the non-wild type (presumed resistance determinants that could be verified by whole-genome sequencing analysis), and the clinical breakpoint. Susceptible, resistant, and intermediate value columns are indicated (45).