Table 5.

Stratification analysis.

Subgroups	No. of patients	TTA (h)	Inflection point (h)	OR (95% CI) P-value <Inflection point	OR (95% CI) P-value >Inflection point	P for log-likelihood ratio test
Age
65<age≤75	667	67.1±153.2	288	1.00 (1.00–1.01) 0.0593	0.99 (0.98–1.01) 0.3913	0.064
75<age≤85	1249	85.9±294.0	2	2807408.17 (0.00–Inf) 0.9822	1.00 (1.00–1.00) 0.1267	0.036
85<age	445	78.4±143.4	336	1.00 (0.99–1.00) 0.2202	1.00 (1.00–1.01) 0.0384	0.047
Sex
Female	1618	79.6±246.8	30	1.04 (1.01–1.06) 0.0048	1.00 (1.00–1.00) 0.6242	0.004
Male	743	78.2±215.0	2	2659279.31 (0.00–Inf) 0.9792	1.00 (1.00–1.00) 0.2129	0.017
aCCI
≤4	1569	67.6±209.9	10	1.10 (1.03–1.18) 0.0061	1.00 (1.00–1.00) 0.4246	0.005
>4	792	102.1±282.3	2	1760342.48 (0.00–Inf) 0.9801	1.00 (1.00–1.00) 0.3862	0.06
Transferred
Yes	1214	138.6±301.7	24	1.01 (0.99–1.04) 0.2113	1.00 (1.00–1.00) 0.1990	0.217
No	1124	12.0±18.9	17	1.07 (1.03–1.12) 0.0007	0.98 (0.95–1.00) 0.0913	<0.001
CHD
Yes	1215	78.4±203.3	8	1.12 (1.02–1.24) 0.0178	1.00 (1.00–1.00) 0.0844	0.041
No	1146	79.9±268.6	2	2554552.96 (0.00–Inf) 0.9818	1.00 (1.00–1.00) 0.9171	0.015
Dementia
Yes	89	107.8±159.2	4	482968.39 (0.00–Inf) 0.9942	1.00 (1.00–1.00) 0.5730	0.267
No	2272	78.0±239.7	9	1.10 (1.03–1.17) 0.0025	1.00 (1.00–1.00) 0.3303	0.002
Time to operation (d)
≤2	558	125.0±354.7	24	1.02 (0.98–1.06) 0.2898	1.00 (1.00–1.00) 0.1347	0.298
>2	1803	65.0±184.6	8	1.14 (1.05–1.23) 0.0020	1.00 (1.00–1.00) 0.8464	0.001
Infusion (ml)
≤1600	1779	72.7±203.7	17	1.03 (1.00–1.06) 0.0358	1.00 (1.00–1.00) 0.1686	0.038
>1600	582	95.3±298.7	7	1.37 (1.10–1.71) 0.0043	1.00 (1.00–1.00) 0.5807	0.002
Stay in hospital (d)
≤7	858	81.9±298.3	11	1.07 (0.98–1.16) 0.1509	1.00 (1.00–1.00) 0.2728	0.146
>7	1503	77.6±194.0	9	1.09 (1.02–1.17) 0.0165	1.00 (1.00–1.00) 0.5486	0.015

Inf, infinity.