FIG. 3.

Sequence characterization of plant-adapted variant TYMV genomes. A diagram of the portions of the TYMV genome encoding the essential replication protein p206 (ORF-206), a movement protein (ORF-69), and coat protein (CP ORF) is shown at the top. The nucleotides marking the beginning and end of each ORF are indicated, as are the nucleotides corresponding to distinct domains within ORF-206: MTR, methyltransferase-like domain; PRO, protease domain; HEL, helicase-like domain; POL, polymerase-like domain. The nucleotide corresponding to the site of proteolytic processing of p206 (1) is indicated with an arrowhead. The lower section of the figure shows the parts of each plant-adapted genome that were sequenced. The identified mutations are indicated with arrows; the nucleotide change is shown above each arrow, and the coding changes are indicated in bold: the coding effects on the movement and coat proteins are shown above the line and, for p206, in italics below the line indicating the genome. An asterisk highlights a coding change.