Table 5.
Risk factors for multidrug−resistant bacterial infections in the training cohort.
| With multidrug− resistant bacteria and fungus (n=105) |
Without multidrug− resistant bacteria and fungus (n=72) |
P | |
|---|---|---|---|
| Age, years (mean, ± SD) | 58.75 ± 15.68 | 52.54 ± 15.90 | 0.010 |
| Gender, n (%) | |||
| Female | 42 | 37 | |
| Male | 63 | 35 | 0.134 |
| Duration of surgery (mean, ± SD) | 203.75 ± 93.93 | 180.32 ± 66.70 | 0.124 |
| Type of surgery | |||
| Emergency operation | 36 | 14 | |
| Selective operation | 69 | 58 | 0.031 |
| Grade of surgery | |||
| III | 63 | 27 | |
| IV | 42 | 35 | 0.256 |
| Secondary surgery | |||
| Yes | 18 | 0 | |
| No | 87 | 72 | <0.001 |
| Categories of gastrointestinal fistula | |||
| colon fistula | 24 | 17 | |
| enteric fistula | 50 | 36 | |
| colon-enteric fistula | 4 | 5 | |
| gastric fistula | 3 | 0 | |
| duodenal fistula | 12 | 1 | |
| others | 12 | 6 | 0.104 |
| With malignant tumors | |||
| Yes | 55 | 34 | |
| No | 50 | 38 | 0.500 |
| With hypertension | |||
| Yes | 12 | 11 | |
| No | 93 | 61 | 0.454 |
| With diabetes | |||
| Yes | 10 | 3 | |
| No | 95 | 69 | 0.180 |
| Clinical outcome | |||
| Survival | 30 | 2 | |
| Death | 75 | 70 | <0.001 |
| ICU stays (mean, ± SD) | 8.55 ± 11.56 | 2.74 ± 4.28 | <0.001 |
| Hospital stays (mean, ± SD) | 58.37 ± 35.82 | 38.83 ± 14.92 | <0.001 |
| Preoperative WBC (×109/L) | 8.72 ± 6.27 | 6.52 ± 3.80 | 0.005 |
| Preoperative N (×109/L) | 7.09 ± 5.92 | 4.45 ± 3.56 | <0.001 |
| Preoperative L (×109/L) | 1.79 ± 8.41 | 1.36 ± 0.65 | <0.001 |
| Preoperative Hb (g/L) | 98.19 ± 20.59 | 107.19 ± 25.12 | <0.001 |
| Preoperative PLT (×109/L) | 217.09 ± 119.18 | 203.36 ± 90.07 | 0.636 |
| Preoperative ALB (g/L) | 33.25 ± 5.81 | 35.70 ± 6.29 | 0.001 |
| Preoperative CRP (mg/L) | 82.96 ± 92.32 | 29.76 ± 41.51 | <0.001 |
| Preoperative TBIL (umol/L) | 22.31 ± 21.70 | 15.00 ± 20.96 | <0.001 |
| Preoperative ALT (U/L) | 36.47 ± 41.88 | 32.10 ± 23.50 | 0.927 |
| Preoperative Cr (umol/L) | 73.88 ± 47.93 | 77.24 ± 80.95 | 0.870 |
| Preoperative PCT (ng/L) | 6.05 ± 19.70 | 0.31 ± 0.41 | <0.001 |
| Preoperative D-dimer (mg/L) | 3.64 ± 4.16 | 1.34 ± 2.85 | <0.001 |
| Postoperative WBC (×109/L) | 13.82 ± 7.63 | 7.14 ± 2.98 | <0.001 |
| Postoperative N (×109/L) | 12.84 ± 10.07 | 6.47 ± 10.17 | <0.001 |
| Postoperative L (×109/L) | 1.00 ± 1.09 | 1.06 ± 0.55 | 0.019 |
| Postoperative Hb (g/L) | 90.41 ± 19.04 | 97.88 ± 14.11 | 0.005 |
| Postoperative PLT (×109/L) | 207.76 ± 132.72 | 221.58 ± 103.38 | 0.176 |
| Postoperative ALB (g/L) | 31.36 ± 6.24 | 35.55 ± 4.31 | <0.001 |
| Postoperative CRP (mg/L) | 126.38 ± 108.72 | 58.73 ± 60.79 | <0.001 |
| Postoperative TBIL (umol/L) | 36.94 ± 47.36 | 22.02 ± 30.85 | <0.001 |
| Postoperative ALT (U/L) | 66.58 ± 174.50 | 38.67 ± 41.37 | 0.365 |
| Postoperative Cr (umol/L) | 82.83 ± 66.68 | 65.38 ± 62.84 | 0.027 |
| Postoperative PCT (ng/L) | 7.02 ± 15.10 | 0.30 ± 0.31 | <0.001 |
| Postoperative D-dimer (mg/L) | 4.91 ± 5.04 | 3.07 ± 1.93 | 0.265 |
The colored values indicate P-values less than 0.05, highlighting statistically significant results.