Table 3.
Stratification analysis of morphological features across different subgroups
| VAO angle§ | V4 length§ | V2 curvature§ | V3 curvature§ | BA length§ | |
|---|---|---|---|---|---|
| Gender | |||||
| Female | 1.05 (0.98, 1.13) 0.1772 | 1.02(0.95, 1.10) 0.5896 | 0.00(0.00,120.90) 0.1793 | 0.02(0.00,1419.30) 0.4891 | 1.09 (0.97, 1.23) 0.1640 |
| Male | 1.05 (0.99, 1.11) 0.1197 | 0.97 (0.89, 1.04) 0.3917 | 0.25 (0.00, 5365.30) 0.7843 | 0.00 (0.00, 95.21) 0.1906 | 1.09 (0.98, 1.22) 0.1232 |
| P for interaction | 0.897 | 0.3023 | 0.3239 | 0.5627 | 0.9882 |
| Dissection location | |||||
| Extracranial | 1.07 (1.01, 1.12) 0.0115 | 0.96 (0.91, 1.01) 0.1308 | 0.00 (0.00, 2.04) 0.0679 | 0.00 (0.00, 7.56) 0.1374 | 1.09 (0.99, 1.19) 0.0662 |
| Intercranial | 0.94 (0.78, 1.12) 0.4628 | 0.97 (0.80, 1.17) 0.7302 | 0.00 (0.00, inf) 0.6188 | 0.59 (0.00, inf) 0.9623 | 1.13 (0.90, 1.42) 0.2881 |
| P for interaction | 0.1369 | 0.9587 | 0.9725 | 0.6577 | 0.7663 |
| Hypertension | |||||
| No | 1.03 (0.97, 1.10) 0.3406 | 1.02 (0.94, 1.11) 0.6219 | 0.00(0.00, 24663.58) 0.4195 | 16.64 (0.00, inf) 0.6987 | 0.99 (0.90, 1.09) 0.8268 |
| Yes | 1.04 (0.98, 1.10) 0.1729 | 0.91 (0.84, 0.99) 0.0375 | 0.02 (0.00, 308.46) 0.4162 | 0.00 (0.00, 1.47) 0.0574 | 1.11 (0.97, 1.27) 0.1204 |
| P for interaction | 0.8129 | 0.0595 | 0.7627 | 0.1154 | 0.1594 |
| Hyperlipidemia | |||||
| No | 1.05 (1.00, 1.09) 0.0304 | 0.97 (0.92, 1.02) 0.2194 | 0.00 (0.00, 6.67) 0.1254 | 0.01 (0.00, 17.62) 0.2252 | 1.08 (0.99, 1.17) 0.0772 |
| Yes | 305950.92(0.00,inf)0.9922 | 72.31 (0.00, inf) 0.9922 | inf (0.00, inf) 0.9922 | 0.00 (0.00, inf) 0.9922 | 0.16 (0.00, inf) 0.9922 |
| P for interaction | 0.1033 | 0.0831 | 0.0682 | 0.2235 | 0.0425 |
| DM | |||||
| No | 1.04 (1.00, 1.09) 0.0389 | 0.97 (0.92, 1.02) 0.1933 | 0.00 (0.00, 7.81) 0.1324 | 0.00 (0.00, 9.42) 0.1682 | 1.06 (0.99, 1.15) 0.1032 |
| Yes | 470.58 (0.00, inf) 0.9922 | 26009.72(0.00,inf)0.992 | 0.00 (0.00, inf) 0.9922 | 0.00 (0.00, inf) 0.9922 | inf (0.00, inf) 0.9922 |
| P for interaction | 0.1105 | 0.0899 | 0.135 | 0.1036 | 0.0966 |
| Morphology subtypes | |||||
| Pearl-and-string appearance | 0.98 (0.81, 1.18) 0.8160 | 0.93 (0.74, 1.17) 0.5446 | 0.00 (0.00, inf.) 0.3641 | 0.08 (0.00, inf.) 0.8290 | 1.13 (0.93, 1.37) 0.2321 |
| Steno-occlusion only | 1.01 (0.96, 1.06) 0.6444 | 0.96 (0.89, 1.03) 0.2105 | 0.00 (0.00, 4.19) 0.0793 | 0.00 (0.00, 48.54) 0.1929 | 1.05 (0.94, 1.18) 0.3723 |
| Aneurysmal dilatation only | 1.11 (1.00, 1.22) 0.0518 | 0.99 (0.92, 1.06) 0.6925 | 252,448.73(0.01,inf)0.1461 | 0.50(0.00,1,059,079.75)0.925 | 1.04 (0.93, 1.17) 0.4981 |
| P for interaction | 0.1732 | 0.7688 | 0.0359 | 0.7386 | 0.7851 |
| VAH | |||||
| None | 1.05 (1.00, 1.10) 0.0446 | 0.97 (0.92, 1.02) 0.2662 | 0.00 (0.00, 13.05) 0.1425 | 0.00 (0.00, 15.86) 0.1916 | 1.07 (0.98, 1.17) 0.1469 |
| Ipsilateral | 1.06 (0.94, 1.20) 0.3632 | 0.94 (0.80, 1.11) 0.4823 | 0.03(0.00,388,166.7)0.663 | 0.00(0.00,164,068.5)0.469 | 0.90 (0.66, 1.23) 0.5002 |
| Opposite | 0.89 (0.61, 1.30) 0.5614 | 1.00 (0.84, 1.18) 0.9689 | 0.03 (0.00, inf) 0.8443 | inf (0.00, inf) 0.6018 | 1.21 (0.80, 1.82) 0.3706 |
| Bilateral | 1.00 (0.00, inf) 1.0000 | 1.00 (0.00, inf.) 1.0000 | 1.00 (0.00, inf) 1.0000 | 1.00 (0.00, inf) 1.0000 | 1.00 (0.00, inf) 1.0000 |
| P for interaction | 0.7328 | 0.9703 | 0.9820 | 0.8038 | 0.5653 |
§variables were expressed as OR (95% CI) P value
*Statistically significant at P < 0.05
DM diabetes mellitus, VAH vertebral artery hypoplasia, OR odds ratio, CI confidence intervals