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. 2024 Dec 11;7(12):e70209. doi: 10.1002/hsr2.70209

Figure 2.

Figure 2

The platelet–neutrophil aggregates (PNA) formation in healthy control and acute coronary syndromes (ACS) patients. (A) Isotype control. (B) Neutrophils were initially gated based on characteristic forward scatter (FSC) and side scatter (SSC), as indicated within the circle. The population of cells co‐expressing CD16 and CD61 markers was identified as PNA, as illustrated in (C and D). (C) An example of the amount of PNA in a healthy control. (D) An example of the amount of PNA in an ACS patient. (E) The density plot, showing the effectiveness of the parameters in distinguishing between patient and healthy groups, the red curve for the patient group and a blue curve for the healthy control group. (F) The box plot showing the comparison of PNA averages in the patient (red box) and healthy volunteers (blue box) (77.88 ± 20.78 in patients vs. 7.82 ± 3.94 in controls, p < 0.001).