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Oligoclonal proliferation of CD8+ T lymphocytes in acute SIV infection. Proliferating fractions of 19 TCR Vβ (Vb) subsets were determined by flow cytometry before and at the peak of proliferation after SIV infection in three rhesus macaques. Asterisks denote Vβ subsets with >25% proliferating fraction and a more than eightfold increase in proliferation following SIV infection. MM, Macacamulatta.
