Table 2. The association of CEA and CA125 with PPF.

Variables	Categorical						Continuous
	Model 1			Model 2			Model 1			Model 2
	OR (95% CI)	P value		OR (95% CI)	P value		OR (95% CI)	P value		OR (95% CI)	P value
CEA	3.42 (1.74–6.72)	<0.001		2.58 (1.36–4.92)	0.004		1.87 (1.19–2.93)	0.006		1.74 (1.13–2.68)	0.01
CA125	1.96 (1.08–3.55)	0.03		1.88 (0.98–3.63)	0.059		1.41 (1.01–1.97)	0.043		1.39 (0.97–2.00)	0.08

Model 1: crude; Model 2: adjusted for DLCO% pred., age, pulmonary hypertension, honeycombing, emphysema. CEA, carcinoembryonic antigen; CA125, carbohydrate antigen 125; PPF, progressive pulmonary fibrosis; OR, odds ratio; CI, confidence Interval; DLCO% pred., percent predicted for diffusion capacity of the lung for carbon monoxide.