Table 3. Analysis of prognostic factors related to mortality in 106 patients with chronic pulmonary aspergillosis.
Characteristics | Univariate | Final multivariate | |||
---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Age | 1.518 (0.628–3.671) | 0.35 | – | – | |
Male sex | 0.023 (0.000–1.057) | 0.053 | – | – | |
Dyspnea | 2.261 (0.929–5.500) | 0.07 | – | – | |
Fever | 1.219 (0.438–3.390) | 0.70 | – | – | |
Hypoalbuminemia | 3.976 (1.608–9.834) | 0.003 | 1.746 (0.617–4.940) | 0.29 | |
Underlying pulmonary condition | 0.818 (0.296–2.258) | 0.70 | – | – | |
Smoking | 2.538 (1.020–6.314) | 0.045 | 1.061 (0.354–3.185) | 0.91 | |
COPD | 1.810 (0.687–4.770) | 0.23 | – | – | |
Lung tuberculosis (activity) | 0.045 (0.000–185.665) | 0.47 | – | – | |
Emphysema | 2.849 (1.164–6.972) | 0.02 | 4.107 (1.414–11.933) | 0.009 | |
Non-tuberculous mycobacterium | 1.151 (0.153–8.637) | 0.89 | – | – | |
Bronchiectasis | 0.425 (0.175–1.032) | 0.059 | – | – | |
Lung cancer | 7.054 (2.649–18.787) | <0.001 | 8.511 (2.494–29.047) | <0.001 | |
Lung tuberculosis scarring | 1.701 (0.643–4.497) | 0.28 | – | – | |
Diabetes | 2.324 (0.831–6.495) | 0.11 | – | – | |
Use of systemic glucocorticoids | 1.516 (0.201–11.441) | 0.69 | – | – | |
Gram-positive bacteria | 1.882 (0.778–4.551) | 0.16 | – | – | |
Gram-negative bacteria | 2.966 (1.180–7.455) | 0.02 | 1.988 (0.748–5.287) | 0.17 |
CI, confidence interval; COPD, chronic obstructive pulmonary disease.