FIG. 3.

Sequence similarities between the P2-V598/80 V/W recombinant strain and two cocirculating wild PVs. A schematic diagram of the genetic organization of the PV genome is shown. The 5′UTR and 3′UTR regions, the genomic regions encoding structural capsid proteins (VP1 through VP4), and those encoding nonstructural proteins (2A through 3D) are shown. The size of the genome in kilobases is also indicated. A schematic diagram of the genome of P2-V/598/80, of the cocirculating strains, and of P2-V/Sabin is given. Sequenced regions are indicated: Sabin 2, ; nonvaccine sequence, □. The sequenced parts of the genome compared are indicated: 5′ UTR, positions 220 to 468; VPI-2A, positions 3295 to 3444; 2C, positions 4546 to 4895; 3D1, positions 6172 to 6371. The percent nucleotide identity between P2-V/598/80, the two epidemic wild PVs, and the P2-V Sabin sequences was calculated after alignment with CLUSTAL W.