FIG. 4.

Uptake of cholera toxin and transferrin into wild-type (WT) and K44A mutant dynamin I-expressing NIH 3T3 cells. NIH 3T3 cells expressing either wild-type (A, B, E, and F) or K44A mutant (C, D, G, and H) dynamin I were incubated with either FITC-Ctx (A to D) or OG-Tfrn (E to H). Uptake of FITC-Ctx is shown in panels B and D, and the corresponding α-caveolin 1 uptake is shown in panels A and C. Uptake of OG-Tfrn is shown in panels F and H, and the corresponding α-clathrin light-chain uptake is shown in panels E and G.