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. 2024 Nov 12;16(11):e73546. doi: 10.7759/cureus.73546

Table 3. Impact of the COVID-19 pandemic on takotsubo syndrome.

P: Pearson chi-square test; L: logistic regression; Ln: linear regression.

P-value < 0.05 indicates statistical significance.

  Pre-COVID-19 pandemic (2017-2018) COVID-19 pandemic (2020-2021) 95% confidence interval P-value
Mortality rate in takotsubo patients (%) 6.04 8.67 - <0.001P
Odds of mortality in takotsubo patients  
-Unadjusted 1 1.47 1.35 - 1.61 <0.001L
-Adjusted with COVID-19 status 1 1.28 1.17 - 1.41 <0.001L
-Adjusted with multiple potential confounders and covariates 1 1.28 1.17 - 1.41 <0.001L
Length of stay (LOS) of takotsubo admissions  
-Mean (days) (95% CI) 6.9 (6.7-7.1) 7.2 (7.1-7.5) - -
-Day increase in LOS 0 0.43 0.15 - 0.70 0.003Ln
-Adjusted with COVID-19 status (days) 0 0.12 -0.16 - 0.39 0.404Ln
-Adjusted with multiple potential confounders covariates (days) 0 -0.004 -0.24 - 0.23 0.975Ln