TABLE 2. Age group, pregnancy status, and infecting serotype among all dengue patients and hospitalized dengue patients — Puerto Rico Department of Health, Puerto Rico, 2010–2019, 2020–2022, and 2023–2024.
| Characteristic |
2010–2019* |
2020–2022* |
2023–2024* |
Total 2010–2024* |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of dengue cases |
No. (%) of hospitalized dengue patients |
No. of dengue cases |
No. (%) of hospitalized dengue patients |
Adjusted* OR (95% CI) |
No. of dengue cases |
No. (%) of hospitalized dengue patients |
Adjusted* OR (95% CI) |
Total no. of dengue cases |
No. (%) of hospitalized dengue patients |
Adjusted* OR (95% CI) |
|
| Age group, yrs† | |||||||||||
| <20 |
15,508 |
6,254 (40.3) |
1,490 |
658 (44.2) |
1.2 (1.0–1.3) |
2,255 |
1,330 (59.0) |
1.5 (1.3–1.7)§ |
19,253
|
8,242 (42.8)
|
1.6 (1.5–1.7)§
|
| 20–39 |
7,142 |
2,121 (29.7) |
692 |
222 (32.1) |
1.1 (1.0–1.3) |
1,681 |
801 (47.7) |
1.8 (1.6–2.1)§ |
9,515
|
3,144 (33.0)
|
Ref
|
| ≥40 |
7,489 |
2,457 (32.8) |
511 |
145 (28.4) |
0.8 (0.6–0.9)§ |
1,946 |
1,013 (52.1) |
1.8 (1.6–2.0)§ |
9,946
|
3,615 (36.3)
|
1.2 (1.1–1.2)§
|
| Unknown |
378 |
76 (20.1) |
2 |
0 (—) |
— |
0 |
0 (—) |
— |
380
|
76 (20.0)
|
—
|
|
Total
|
30,517
|
10,908 (35.7)
|
2,695
|
1,025 (38.0)
|
1.1 (1.0–1.2)
|
5,882
|
3,144 (53.5)
|
1.7 (1.5–1.8)
§
|
39,094
|
15,077 (38.6)
|
—
|
|
Pregnant patients
|
276 |
103 (37.3) |
20 |
6 (30.0) |
— |
22 |
8 (36.4) |
— |
318
|
117 (36.8)
|
—
|
|
Serotype†
| |||||||||||
| DENV-1 |
15,039 |
5,360 (35.6) |
1,404 |
521 (37.1) |
1.1 (1.0–1.2) |
1,629 |
855 (52.5) |
2.2 (2.0–2.4)§ |
18,072
|
6,736 (37.3)
|
Ref
|
| DENV-2 |
635 |
173 (27.2) |
89 |
37 (41.6) |
1.9 (1.2–3.0)§ |
940 |
626 (66.6) |
5.3 (4.3–6.7)§ |
1,664
|
836 (50.2)
|
1.5 (1.3–1.7)§
|
| DENV-3 |
5 |
1 (20.0) |
18 |
9 (50.0) |
4.2 (0.5–93.0) |
2,183 |
1,333 (61.1) |
6.6 (1.0–130.6) |
2,206
|
1,343 (60.9)
|
1.8 (1.6–2.0)§
|
| DENV-4 |
5,104 |
1,743 (34.1) |
1 |
1 (100.0) |
— |
1 |
0 (—) |
— |
5,106
|
1,744 (34.2)
|
1.0 (0.9–1.0)
|
| Unknown |
9,734 |
3,631 (37.3) |
1,183 |
457 (38.6) |
— |
1,129 |
330 (29.2) |
— |
12,046
|
4,418 (36.7)
|
—
|
| Total | 30,517 | 10,908 (35.7) | 2,695 | 1,025 (38.0) | 1.1 (1.0–1.2) | 5,882 | 3,144 (53.5) | 1.7 (1.5–1.8) § | 39,094 | 15,077 (38.6) | — |
Abbreviations: DENV = dengue virus; OR = odds ratio; Ref = referent group.
* Each row in the first three columns (2010–2019, 2020–2022, and 2023–2024) represents the number and percentage of hospitalizations among cases in each age group or serotype, with adjusted ORs comparing proportions in 2020–2022 and 2023–2024 with those from 2010–2019 (Ref ). Age group ORs are adjusted by serotype. Serotype ORs are adjusted by age group. The “Total (2010–2024)” column represents a separate analysis comparing all hospitalized dengue patients during 2010–2024 with Ref categories for age group (20–39 years) and serotype (DENV-1).
† Percentages of overall hospitalized dengue patients are calculated among those for whom information on age and DENV serotype were known.
§ Statistically significant increase or decrease in odds of hospitalization compared with 2010–2019.