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. 2024 Dec 12;13:RP96150. doi: 10.7554/eLife.96150

Figure 1. Clonal hematopoiesis of indeterminate potential (CHIP), mosaic loss of Y chromosome (mLOY) and their combination are as frequent in myocardial infarction (MI)(+) and MI(-) subjects.

(A) Prevalence of CHIP, mLOY, and their combination in the total cohort of 449 subjects, in MI(+) as well as in MI(-) subjects. (B) Mutational spectrum of CHIP expressed as the proportion of mutations detected in the indicated genes. (C) Variant allele frequency (VAF) measured for the different mutations detected in the 449 subjects detected in the indicated genes. (D) Prevalence of CHIP and mLOY depending on age in the total cohort (for CHIP) and in male subjects (for mLOY).

Figure 1.

Figure 1—figure supplement 1. Variant allele frequency (VAF) of somatic mutations detected in myocardial infarction (MI)(+) and MI(-) subjects.

Figure 1—figure supplement 1.

The graph represents the VAF measured for the different mutations detected in MI(+) and MI(-) subjects in the indicated genes.