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. 2024 Dec 12;13:RP96150. doi: 10.7554/eLife.96150

Table 3. CHIP and mLOY are not associated with an increased atherosclerotic burden.

Atherosclerosis burden evaluation in MI(+) subjects
All patients (n=149) CHIP (-) (n=70) CHIP (+) (n=79) p-value mLOY (-) (n=53) mLOY (+) (n=44) p-value
Multitroncular lesions, n (%) 68 (45.6) 29 (41.4) 39 (49.4) 0.484 25 (47.2) 20 (45.4) 0.717
Carotid stenosis ≥50%, n (%) 7 (4.7) 2 (2.8) 5 (6.3) 0.317 2 (3.8) 3 (6.8) 0.451
Global atheroma volume (mm3), median (Q1;Q3) 499.5 (408.0;604.5) 455.0 (374.0;555.0) 520.0 (411.5;611.5) 0.333 601.0 (412.0;718.0) 492.0 (344.5;600.5) 0.707
Atherosclerosis burden evaluation in MI(-) subjects
All patients (n=297) CHIP (-) (n=175) CHIP (+) (n=122) p-value mLOY (-) (n=84) mLOY (+) (n=39) p-value
Patients with atherosclerotic plaque, n (%) 135 (45.4) 81 (46.3) 54 (44.3) 0.997 34 (40.5) 19 (48.7) 0.537
Number of plaque, median (Q1;Q3) 1 (1;2) 2 (1;2) 1 (1;2) 0.258 2 (1;2) 2 (1;2) 0.863
Intima Media Thickness (mm), median (Q1;Q3) 0.68 (0.60;0.76) 0.67 (0.60;0.76) 0.68 (0.59;0.74) 0.897 0.67 (0.62;0.76) 0.72 (0.57;0.83) 0.706

Data are expressed as numbers and frequency or median, first and third quartiles. For quantitative values, comparisons were made by linear regression of log values adjusted for age and sex. For qualitative parameters, comparisons were made by the fisher test and logistic regression. For each variable, results are expressed among patients with available value.