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Mutations in the BTV-10 VP7 gene and their effect on trimer and CLP formation
| BTV-10 VP7 mutant | Trimer formation | CLP assembly | CLP stability in CsCl gradient |
|---|---|---|---|
| E104W | Yes | Yes | Yes |
| R111F | Yes | Yes | No |
| W119D | Yes | Yes | No |
| F268R | Yes | Yes | Yes |
| Y271Ra | No | No | No |
| D318N | Yes | Yes | Yes |
| T321R | Yes | Yes | No |
Note that this mutant failed to form trimers or assemble CLPs.
