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. 2024 Nov 29;14:1492465. doi: 10.3389/fonc.2024.1492465

Table 4.

PNS detection comparison between 3D LAVA_Flex and T1WI ce in T3 and T4 stage nasopharyngeal carcinoma.

Level T1WI ce
3D LAVA_Flex
T1WI ce Total MB test
Nerve negative positive P-value
1 mandibular nerve negative 35 0 35 0.016
positive 6 10 16
Total 41 10 51
1 maxillary nerve negative 40 0 40 0.125
positive 3 8 11
Total 43 8 51
1 cavernous sinus (CN III–V) negative 40 0 40 0.500
positive 1 10 11
Total 41 10 51
2 anterior CNs negative 25 0 25 0.063
positive 4 22 26
Total 29 22 51
1 hypoglossal nerve negative 37 0 37 0.008
positive 7 7 14
Total 44 7 51
1 jugular foramen (IX–XI nerves) negative 44 0 44 0.125
positive 3 4 7
Total 47 4 51
1 carotid space (IX–XII, primary lesion and/or lymph nodes) negative 25 0 25 0.001
positive 17 9 26
Total 42 9 51
2 posterior CNs negative 37 0 37 0.016
positive 6 8 14
Total 43 8 51
3 individual level
(all above)
negative 22 0 22 0.031
positive 5 24 29
Total 27 24 51

PNS, perineural spread; CN, cranial nerve; 3D LAVA_Flex, three-dimensional liver acquisition with volume acceleration-flexible; CE, contrast enhancement; MB, McNemar Bowker.