Table 1.
Characteristics and status of patients with spheno-orbital tumors treated by the single-step approach
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 | Patient 11 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex | Female | Female | Female | Female | Female | Female | Female | Female | Female | Female | Female |
| Age at surgery | 46 | 53 | 52 | 19 | 62 | 53 | 46 | 56 | 65 | 50 | 72 |
| Previous surgeries | None | Biopsy | None | Biopsy | 3 | 2 | 2 | 2 | None | None | 1 |
| Histology | Meningioma* | Meningioma* | Meningioma* | Fibrous Dysplasia | Dermoid Cyst | Meningioma* | Meningioma* | Meningioma* | Meningioma* | Meningioma* | Meningeoma* |
| Leading signs or symptoms | Exophthalmos | Exophthalmos | Exophthalmos | Exophthalmos | Headache | Facial pain | Exophthalmos | Exophthalmos | Exophthalmos | Exophthalmos | Soft tissue swelling |
| EI prä OP | 1,55 | 1,39 | 1 | 1,12 | 1,17 | N/A | 1,36 | N/A | 1,39 | 1,43 | 1,15 |
| EI early post OP | 1,36 | 1,91 | 1,05 | 1 | 1,16 | N/A | 1,23 | N/A | 1,15 | 1,61 | 1,07 |
| EI last follow up | 1,36 | 1,41 | 0,87 | 1 | 1,07 | N/A | 1,2 | N/A | 1,11 | 1,21 | 1,07 |
| 1-month postoperative leading symptoms | Improved | Improved | Improved | Improved | Improved | Unchanged | Improved | Improved | Improved | Improved | Worsened |
| Preoperative KPS | 80 | 80 | 80 | 80 | 90 | 60 | 80 | 60 | 60 | 80 | 60 |
| 1-month KPS | 90 | 90 | 90 | 60 | 100 | 60 | 70 | 70 | 70 | 90 | 50 |
| 6-months KPS | 100 | 100 | 90 | LTFU | 100 | 60 | 80 | 80 | 90 | Not reached yet | Not reached yet |
| Preoperative deterioration in vision | No | No | No | No | No | Yes | No | Yes | No | Yes | No |
| 1-month postoperative vision | Unchanged | Unchanged | Unchanged | Worse | Unchanged | Unchanged | Worse | Unchanged | Unchanged | Improved | Unchanged |
| Postoperative complication | None | None | None | Intraorbital hematoma | Impaired wound-healing | None | Visual acuity deterioration | None | Impaired Wound healing | None | Pneumonia |
| Surgical site infection | No | No | No | No | Yes | No | No | No | No | No | No |
| Adjuvant therapy | None | None | Radiotherapy | None | None | Radiotherapy | None | None | None | None | None |
| Revision surgery | No | No | No | Yes | Yes | No | Yes | No | Yes | No | No |
| 6-months tumor recurrence | No | No | No | LTFU | No | Yes | No | No | No | Not reached yet | Not reached yet |
KPS Karnofsky performance status scale, LTFU lost to follow up, N/A not applicable (due to a planned orbital exenteration); *All Meningiomas were graded as central nervous system (CNS) World Health Organization (WHO) grade 1