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. 2024 Dec 12;272(1):35. doi: 10.1007/s00415-024-12737-y

Table 3.

Diagnostic performance of different tests in the assessment of myopathy

Investigation n Sensitivity (%) Specificity (%) PPV (%) NPV (%)
CK 627 54.5 77.8 55.8 76.9
Myositis antibodies 114 34.3 95.1 92.6 44.8
EMG 702 73.5 90.6 76.1 89.3
Muscle MRI 150 70.5 79.0 82.7 65.3
Biopsy 294 72.5 84.8 83.1 75.0
Genetics 176 37.0 75.7 51.9 62.9

Note: we have not included MRI neuroaxis as, although this was commonly requested, the test was not looking for evidence of myopathy but rather to exclude structural pathologies