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Changes in serum TNF-α, IL-1β, Interleukin-1β and IL-10 and pancreas mRNA expression of NF-κB in normal, diabetic control and diabetic treated groups. Values, which have different superscript symbols (a, b, c and d) for each parameter, are significantly different at p < 0.05. MSCs-CMT, MSCs-CM injected daily into tail vein; MSCs-CMP, MSCs-CM injected directly in pancreas, TNF-α, tumor necrosis factor-alpha; IL-1β, interleukin-1beta; IL-10, interleukin-10; NF-κB, nuclear factor kappa-B.
