Table 2.

Incidence of adverse events occurring in more than 5% of patients.

Adverse eventa	Grade	Vitamin D N = 137 (%)	Placebo N = 72 (%)
Fatigue	1	38 (28)	17 (24)
	2	3 (2)	2 (3)
Infusion related reaction	1	10 (7)	5 (7)
	2	40 (29)	17 (24)
	3	0 (0)	1 (1)
Injection site reaction	1	12 (9)	6 (8)
	2	3 (2)	3 (4)
Abdominal pain	1	10 (7)	3 (4)
	2	1 (1)	0 (0)
Constipation	1	8 (6)	4 (6)
	2	2 (1)	0 (0)
Diarrhea	1	8 (6)	2 (3)
	2	0 (0)	2 (3)
Nausea	1	8 (6)	5 (7)
	2	2 (1)	2 (3)
Infection—COVID-19	1	5 (4)	4 (6)
	2	3 (2)	4 (6)
	3	3 (2)	1 (1)
	5	1 (1)	0 (0)
Upper respiratory infection	1	3 (2)	2 (3)
	2	8 (6)	6 (8)
Arthralgia	1	10 (7)	4 (6)
	2	2 (1)	2 (3)
Back pain	1	12 (9)	3 (4)
	2	3 (2)	3 (4)
Pain in extremity	1	8 (6)	4 (6)
Headache	1	16 (12)	4 (6)
	2	2 (1)	1 (1)
	3	1 (1)	0 (0)
Cough	1	10 (7)	4 (6)
	2	1 (1)	0 (0)
Dyspnea	1	5 (4)	4 (6)
	2	2 (1)	0 (0)
Pruritus	1	3 (2)	4 (6)
	2	4 (3)	0 (0)
Hypertension	1	6 (4)	1 (1)
	2	7 (5)	4 (6)
	3	3 (2)	0 (0)

^aPatients appear only once in each row.