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. 2024 Nov 20;29:101350. doi: 10.1016/j.mtbio.2024.101350

Fig. 6.

Fig. 6

AntagomiR-150-5p delivery abolished the upregulation of NF-κB (p65), MMP-2, and MMP-9, and reversed the downregulation of Notch3 and elastin expression in the aortas of AAA rats. (A). Representative Western blot bands and analysis of NF-κB (p65), MMP-2, MMP-9, Notch3 and elastin in Cacl2-induced AAA model. (B). Quantitative analysis of NF-κB (p65), MMP-2, MMP-9, Notch3 and elastin in Cacl2-induced AAA model, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 Vs. sham group; #P < 0.05, ##P < 0.01 Vs. AAA group. (C). Representative Western blot bands of NF-κB (p65), MMP-2, MMP-9, Notch3 and elastin in elastase-induced AAA model. (D). Quantitative analysis of NF-κB (p65), MMP-2, MMP-9, Notch3 and elastin in elastase-induced AAA model, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 Vs. sham group; #P < 0.05, ##P < 0.01, ###P < 0.001 Vs. AAA group.