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. 2024 Nov 20;29:101350. doi: 10.1016/j.mtbio.2024.101350

Fig. 8.

Fig. 8

MiR-150-5p regulated the expression of MMP-2, MMP-9, NF-κB (p65) and elastin via Notch3 in VSMCs with TNF-α treatment. (A). Representative Western blot bands of NF-κB (p65), MMP-2, MMP-9, Notch3 and elastin in shR-VSMCs with miR-150-5p inhibition and TNF-α treatment. (B). Quantitative analysis of NF-κB(p65), MMP-2, MMP-9, Notch3 and elastin in shR-VSMCs with miR-150-5p inhibition and TNF-α treatment. ∗∗∗P < 0.001 Vs. N group; #P < 0.05, ##P < 0.01 Vs. shR NC + miR-150inhibitor NC + TNF-α group; +P<0.05, ++P<0.01 Vs. shR Notch3 + miR-150inhibitor NC + TNF-α group; N, normal VSMCs; shR NC, VSMCs transfected GFP lentiviral vector; shR Notch3, VSMCs transfected shR-Notch3 lentiviral vector.