FIG. 2.
Tetrameric Mamu-DR*W201–p46 complex binds specifically to a p46-specific CD4+ T-cell line generated from PBMCs of a Mamu-DR*W201+ rhesus monkey. The p46 tetramer was used to stain two HIV-1 Env-specific T-cell lines generated from PBMCs of the same rhesus monkey, one specific for p46 and the other specific for the p14 Env peptide. Flow-cytometric analysis was performed on gated CD4+ CD3+ T cells.