TABLE 1.
Animal | SIV strain or immunizationa | % Tetramer-binding cellsb | % α4β7+ of:
|
|
---|---|---|---|---|
Tetramer+ cellsc | CD3+ CD8+ T cellsd | |||
118.87 | Δnef | 0.28 | 36 | 41 |
353.88 | Δnef | 0.31 | 58 | 73 |
71.88 | Δnef | 0.56 | 46 | 60 |
313.91 | Δ3 | 0.95 | 84 | 79 |
96118 | DNA i.d./MVA i.d. | 1.69 | 5 | 67 |
96123 | DNA i.d./MVA i.d. | 0.77 | 5 | 42 |
94004 | DNA i.d./MVA i.d. | 9.10 | 6 | 41 |
19777 | Wild-type SIVmac | 0.93 | 81 | 62 |
95114 | Wild-type SIVmac | 0.32 | 22 | 36 |
158.87 | Uninfected | 0.03 | 0 | 78 |
i.d., intradermal.
Percentage of Mamu-A*01/p11C,C→M tetramer-binding cells in PBMC determined after gating on CD3+ CD8+ lymphocytes.
Percentage of CD3+ CD8+ tetramer-binding cells that also express α4β7 integrin.
Percentage of all CD3+ CD8+ lymphocytes that express α4β7.