Table 3.

Genetic correlations with female infertility and enrichment of female infertility cases among four disorders affecting female reproduction

Phenotype	N affected individuals	rg (95% CI)	p value (rg)	Enrichment	p value (Enrichment)
Endometriosis	20,190	0.46 (0.35–0.58)	2.69 × 10−15	3.83	<1 × 10−324
Endometriosis ASRM stages 3 and 4	10,127	0.48 (0.35–0.61)	1.76 × 10−13	5.53	<1 × 10−324
Leiomyoma of uterus	42,107	0.30 (0.19–0.41)	8.78 × 10−8	1.44	1.01 × 10−73
Polycystic ovarian syndrome (PCOS)	2,214	0.22 (0.04–0.39)	0.014	9.27	<1 × 10−324

rg, genetic correlations with female infertility; Enrichment, enrichment of female infertility cases.