Skip to main content
. Author manuscript; available in PMC: 2024 Dec 13.
Published in final edited form as: Kidney Int. 2022 Oct;102(4):694–696. doi: 10.1016/j.kint.2022.06.028

Figure 1. Diagram showing patient cohort and experimental strategy used to determine compartment-specific gene expression.

Figure 1.

Kidney biopsy tissue from Class III or IV (+/− V) lupus nephritis patients, obtained at flare and following induction immunosuppression, was submitted for laser capture microdissection (LCM) followed by assessment of gene expression using an immunology probe set. Healthy kidney tissue was obtained from pre-implantation living donor kidney biopsies was used as a control. Differential gene expression in renal responders and non-responders was examined to identify molecular pathways of treatment response.