FIGURE 2.

Cardiac CLU levels are positively correlated to cardiac hypertrophy induced by transverse aortic constriction. (A) Quantification by qPCR of mRNA levels of genes involved in hypertrophy in sham (n = 7) and TAC (n = 14) mice: Anp (atrial natriuretic peptide), Bnp (brain natriuretic peptide), and β/α‐Mhc (beta and alpha myosin heavy chain). Hprt was used for normalisation. Statistical significance was determined by the Wilcoxon‐Mann Whitney test. **p < 0.01, and ***p < 0.001. (B) Correlation between intraventricular Clu mRNA levels and those of Anp, Bnp, and β/α‐Mhc. Correlations were carried out by the Spearman correlation test. Results were considered statistically significant if the p < 0.05.