Table 2.

Upregulated lncRNAs and circRNAs mediating TKI-resistance in HCC.

lncRNAs	Target	Mechanism	References
MALAT1	miR-140-5p	Increased Aurora kinase A	[134]
THOR	β-catenin	Stabilizes β-catenin and increases CSCs	[135]
NEAT1	miR-335	Activates c-MET and AKT pathways	[136]
TRERNA1	miR-22-3p	Increased NRAS and activation of RAF/MEK/ERK pathway	[137]
LINC-ROR	miR-876-5p	Increased FOXM1	[138]
ZFAS1	Not identified	Increased stemness and EMT	[139]
linc-VLDLR	Not identified	Increased ABCG2	[140]
BBOX1-AS1	miR-361-3p	Increased PHF8	[141]
URB1-AS1	Ferritin	Inhibition of ferroptosis	[142]
circRNA-SORE	miR-103a-2-5p and miR-660-3p; YBX1	Activation of Wnt/β-catenin signaling pathway; stabilization of YBX1	[143,144]
circFOXM1	miR-1324	Increased MECP2	[145]
circDCAF8	miR-217	Increased NAP1L1	[146]