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. 2024 Nov 22;13(23):1938. doi: 10.3390/cells13231938

Table 1.

Screening of anti-inflammatory activity of seaweed samples against COX-1 and COX-2.

Sample IC50 Value (µg/mL) Selectivity Index, SI
COX-1 COX-2
C.L. 48.96 42.74 1.06
M.L. 46.35 40.06 0.88
C.F. 47.41 42.27 1.58
M.F. 44.59 40.01 0.83
R.D. 49.64 45.19 1.07

Seaweed samples used were crude laminarin (C.L.), MWCO 10 kDa laminarin fraction (M.L.), crude fucoidan (C.F.), MWCO 10 kDa fucoidan fraction (M.F.), and reference drug (diclofenac sodium) as R.D.