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Analysis of the impact of HDAC inhibitors on the clonogenic survival of HNSCC cells post-irradiation. (A,D) FaDu, (B,E) A253, and (C,F) UMSCC11b treated with mocetinostat, CUDC-101, or pracinostat (all 1 µM) in comparison to DMSO as a control and clonogenic survival of cells with increasing doses of X-ray irradiation was analysed with three independent experiments. Shown is the mean surviving fraction ± SE. * p < 0.05, ** p < 0.0005, *** p < 0.0001, analysed with the LQ model.
