Table 4.

Consequences of the individual RNAi interventions in GK, EPI and FIB cells on various protein residual activities by Western blot, presented in mean values (MV) and p-values.

Western Blot		FIBs					EPIs					GKs
		KRT5-RNAi	KRT14-RNAi	IVL-RNAi	VIM-RNAi	nt-RNAi	KRT5-RNAi	KRT14-RNAi	IVL-RNAi	VIM-RNAi	nt-RNAi	KRT5-RNAi	KRT14-RNAi	IVL-RNAi	VIM-RNAi	nt-RNAi
MV	KRT5	-	-	-	-	-	0.19 ****	1.60 ns	1.16 ns	1.13 ns	1.00	0.16 ****	0.59 **	0.99 ns	0.85 ns	1.00
	KRT14	-	-	-	-	-	-	-	-	-	-	1.06 ns	0.14 ****	1.12 ns	0.77 *	1.00
	VIM	0.80 ns	0.70 *	0.73 *	0.51 ****	1.00	0.63 ***	0.63 ns	0.24 ****	0.00 ****	1.00	-	-	-	-	-
	IVL	1.14 ns	0.97 ns	0.22 ****	0.82 ***	1.00	0.69 **	0.56 ***	0.08 ****	0.36 ****	1.00	0.50 *	0.24 **	0.07 ****	0.63 ns	1.00
	LOR	1.07 ns	0.77 *	1.53 *	1.37 ns	1.00	0.64 ***	0.64 *	0.80 ns	0.92 ns	1.00	1.28 *	1.01 ns	1.32 ns	1.09 **	1.00
	CDH1	-	-	-	-	-	0.65 *	0.87 ns	0.74 ns	0.44 **	1.00	0.71 *	0.72 *	1.32 **	1.05 ns	1.00
	ITGB1	1.26 ns	1.24 ns	1.18 ns	1.09 *	1.00	3.71 ns	2.33 ns	2.89 *	1.61 *	1.00	1.74 ns	0.62 ns	1.89 ns	2.80 ns	1.00
	ITGB3	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
	YAP	1.04 ns	0.81 *	1.04 ns	1.10 ns	1.00	1.20 ns	1.28 ns	1.29 ns	1.15 ns	1.00	0.63 *	0.93 ns	1.16 ns	1.04 ns	1.00
	LMNB1	0.90 **	0.88 ns	1.33 *	0.92 ns	1.00	0.77 *	1.00 ns	0.78 ns	0.77 ***	1.00	0.56 **	1.10 ns	1.07 ns	0.79 *	1.00
	ARP2/3	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
Expression		>2		>1.5		>1			=1		<1		<0.5		<0.1
p-values		ns = not significant				* = p < 0.05			** = p < 0.01		*** = p < 0.001			**** = p < 0.0001