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Biosynthesis of aminonucleosides. (A) Structures of Cst and related compounds. Nucleoside cores are highlighted in orange, while peptidyl fragments are marked in blue. (B) The suggested cst BGC (Orf1-Orf20) with some proposed functions and the comparison with pur BGC from Streptomyces alboniger strain ATCC 12461 sequence (NZ_CP023695.1). (C) The proposed biosynthetic pathway of Cst.
