Figure 2.

RA mitigated DfE-induced pathological features and mast cell infiltration into the skin and ear lesions of the mice. Representative images of (a) H&E staining and (b) TB staining of skin and ear tissue sections. Epidermal thickness and mast cell numbers were analyzed in the mouse skin at 40× magnification (upper panel) and 400× magnification (lower panel) via microscopy, as shown in the accompanying bar graph on the left. The data are presented as the means ± SEMs (n = 5). # p < 0.05 and ### p < 0.001 vs. the normal control group (CON); * p < 0.05, ** p < 0.01, and *** p < 0.001 vs. DfE. Scale bar = 100 μm.