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. 2024 Nov 24;25(23):12621. doi: 10.3390/ijms252312621

Figure 3.

Figure 3

Domains and PTM sites of c-Myc. (a) Domain structure and interaction partners of c-Myc (N-terminal transactivation domain TAD including MBI and MBII partner interaction domains, nuclear localization sequence (NLS) and an intrinsically disordered C-terminal region containing the bHLHZip domain together with the binding sites of its key partners MAX, MIZ1, ARF, and SKP. (b) Known phosphorylation and acetylation sites of c-Myc according to UniProt data (http://www.uniprot.org/ (accessed on 20 September 2024)).