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. 2024 Dec 2;25(23):12962. doi: 10.3390/ijms252312962

Figure 3.

Figure 3

Effect of HCA preconditioning on cardiac I/R-induced changes in cardiac surface microcirculation. (A) Representative responses of cardiac microcirculation to cardiac I/R in the three groups of rats. (B) Statistical data of cardiac surface microcirculation. Significant decrease in cardiac microcirculation is observed in I/R group vs. sham group, whereas cardiac microcirculation is restored in HCA+I/R group. (C) Cardiac surface blood flow responses to baseline, 1 h of ischemia, and 4 h of reperfusion among the three groups. (D) Mean percentage change in cardiac surface blood flow during ischemia and reperfusion among the three groups. All data are expressed as mean ± SEM (n = 6). * indicates significance vs. sham group (** p < 0.01; *** p < 0.001). # indicates significance vs. I/R group (#### p < 0.0001).