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. 2024 Nov 28;12(23):2390. doi: 10.3390/healthcare12232390

Table 2.

Risk estimates of small-for-gestational-age infants among patients with RA and JIA, stratified by ART use during pregnancy.

Patient Subgroups Proportion with SGA (%) Crude Model Adjusted Model *
Odds Ratio (OR) 95% CI p-Value OR 95% CI p-Value
No RA and JIA 13,025/501,285 (2.6) 1.00 Reference 1.00 Reference
RA and JIA 87/2206 (3.9) 1.54 1.23, 1.90 <0.001 1.47 1.16, 1.83 <0.001
  • -

    CCS

24/264 (9.1) 3.75 2.40, 5.58 <0.001 3.44 2.14, 5.25 <0.001
  • -

    HCQ

3/43 (7.0) 2.81 0.68, 7.74 0.084 3.12 0.74, 8.80 0.062
  • -

    SSZ

14/242 (5.8) 2.30 1.28, 3.80 0.002 2.28 1.22, 3.88 0.005

* Adjusted for maternal age, maternal body mass index, smoking status, income status, race, parity, birth year, pre-pregnancy hypertension, pre-pregnancy diabetes, and co-medication use during pregnancy. CCS: Corticosteroids; HCQ: hydroxychloroquine; SSZ: sulfasalazine. Bold values denote statistical significance at the p < 0.05 level.