Table 1.
Clinical characteristics of the training cohort (FLEMENGHO).
| Characteristics | Controls (N = 52) |
Cases (N = 63) |
p-Value | |
|---|---|---|---|---|
| Anthropometrics | ||||
| Age, years | 62 ± 8 | 66 ± 8 | 0.01 | |
| Females, n (%) | 21 (40.4) | 19 (30.2) | 0.25 | |
| BMI, kg/m2 | 26.3 ± 3.8 | 27.2 ± 2.8 | 0.16 | |
| Estimated lean body mass, kg | 48.4 ± 9.9 | 48.4 ± 8.7 | 1.00 | |
| Systolic blood pressure, mmHg | 139.7 ± 18.6 | 139.4 ± 21.2 | 0.94 | |
| Diastolic blood pressure, mmHg | 84.7 ± 9.5 | 80.7 ± 10.5 | 0.03 | |
| Medications | ||||
| Anti-hypertensive drugs, n (%) | 15 (28.8) | 37 (58.7) | 0.001 | |
| Beta-blockers, n (%) | 4 (7.7) | 17 (27.0) | 0.01 | |
| Calcium channel blockers, n (%) | 7 (13.5) | 13 (20.6) | 0.31 | |
| ACE/ANGR1 blockers, n (%) | 9 (17.3) | 19 (30.2) | 0.11 | |
| Diuretics, n (%) | 3 (5.8) | 16 (25.4) | 0.005 | |
| Statins, n (%) | 12 (23.1) | 26 (41.3) | 0.04 | |
Data are presented as means ± standard deviations or numbers of subjects (%). Abbreviations: body mass index (BMI); angiotensin-converting enzyme (ACE); angiotensin receptor type 1 (ANGR1). p-values lower than 0.01 are bolded.