Table 1.
Demographic summary of the study population.
| Prospective Cohort | Retrospective Cohort | |||||
|---|---|---|---|---|---|---|
| Probands Meeting NCCN 2021.2 Criteria for HBOC | Probands Not Meeting NCCN 2021.2 Criteria for HBOC | |||||
| Number (n) | Percentage (%) | Number (n) | Percentage (%) | Number (n) | Percentage (%) | |
| Gender | ||||||
| Female | 440 | 95.03% | 46 | 92% | 47 | 100% |
| Male | 23 | 4.97% | 4 | 8% | 0 | 0% |
| Cancer type | ||||||
| Breast | 407 | 87.9% | 46 | 92% | 44 | 93.62% |
| Male breast | 6 | 1.3% | 0 | 0% | 0 | 0% |
| Ovarian | 26 | 5.62% | 0 | 0% | 3 | 6.38% |
| Pancreatic | 15 | 3.24% | 0 | 0% | 0 | 0% |
| Prostate | 9 | 1.94% | 4 | 8% | 0 | 0% |
| Age of onset | ||||||
| ≤40 years | 107 | 23.11% | 0 | 0% | 19 | 40.43% |
| >40 years | 355 | 76.67% | 50 | 100% | 28 | 59.57% |
| not available | 1 | 0.22% | 0 | 0% | 0 | 0% |
Abbreviations: NCCN: National Comprehensive Cancer Network; HBOC: hereditary breast and ovarian cancer.