Table 4.
Clinical results of two-stage revision with antibiotic-impregnated CHA for the treatment of PJI.
| Case | Sex | Age | Antibiotics in the CHA Blocks (Numbers) | Antibiotics at Interim Period (Weeks) |
Interim Period (Weeks) | Antibiotics in the CHA Blocks (Numbers) | Antibiotics at Interim Period (Weeks) |
Interim Period (Weeks) | Success /Failure |
|---|---|---|---|---|---|---|---|---|---|
| Removed Implantation | Reimplantation (Two-Stage Exchange) | ||||||||
| 2 | F | 69 | VCM, CTM (20) | FMOX, ABK, GM, VCM, TEIC | 8 | VCM (5) | GM, AMK | 2 | Success |
| 3 | F | 52 | VCM, AMK, MINO (20) | ABPC, CLDM, PIPC, IPM/CS | 6 | FMOX, IPM/CS (5) | FMOX, IPM/CS | 3 | Success |
| 6 | F | 65 | CZOP, CTM, FMOX (36) | CZOP, CTM, FMOX | 3 | - | FMOX, CZP | 2 | Success |
| 7 | F | 67 | CTM, AMK (20) | GM, CMZ, ABK, VCM | 4 | - | FMOX, ABPC/SBT, AMK | 2 | Success |
| 8 | M | 66 | FOM, MCZ, TEIC | PIPC, MCZ | 3 times of irrigation and debridement | TEIC, MCZ (2) | CEZ, ABK, TEIC, CFPN, CTRX, VCM, MEPM | 10 | Success |
| 9 | M | 58 | FOM, IPM/CS (30) | CTRX, CZP | 3 | IPM/CS (2) | CTRX, CZP | 2 | Success |
| 10 | M | 35 | VCM, AMK (30) | VCM, ABK | 6 | VCM (2) | VCM, ABK | 2.5 | Success |
| 11 | M | 62 | VCM, AMK (16) | CZP, PIPC | 9 | VCM (2) | CEZ | 2 | Success |
F, female; M, male; I&D, irrigation and debridement. CTM, cefotiam; AMK, amikacin; FMOX, flomoxef; VCM, vancomycin; MINO, minocycline; IPM/CS, imipenem/cilastatin; PCG, benzylpenicillin; ABK, arbekacin; GM, gentamicin; TEIC, teicoplanin; ABPC, ampicillin; CLDM, clindamycin; PIPC, piperacillin; SBTPC, sultamicillin; CEZ, cefazolin; MEPM. Meropenem; RFP, rifampicin; ABPC/SBT, ampicillin/sulbactam; LVFX, levofloxacin.