Table 3.
Statistically significant liver tissue fatty acids and ratios that contribute to the discrimination between the healthy controls and patients with NASH and NAFL–NASH patient groups. p-values, adjusted p* values and Log2FC for each fatty acid and ratio are provided as well. p-values that correspond to ≤0.05 are bolded. The CV% values for FA 16:0, FA 16:1 and FA 18:3 n6 were 10.2%, 7.68% and 8.27%, respectively.
| Fatty Acids and Fatty Acid Ratios | Adjusted p* Values | Control–NASH | NAFL–NASH | ||
|---|---|---|---|---|---|
| p Value | Log2FC | p Value | Log2FC | ||
| Δ9-Desaturase (FA 16:1/FA 16:0) |
4.84 × 10−3 | 4.79 × 10−3 | 2.59 | 5.01 × 10−2 | 2.23 |
| Δ9- Desaturase (FA 18:1/FA 18:0) |
1.37 × 10−2 | 1.78 × 10−3 | 3.28 | 1.03 × 10−1 | 2.17 |
| FA 16:0 | 4.92 × 10−2 | 3.29 × 10−2 | 1.88 | 1.44 × 10−2 | 1.79 |
| FA 16:1 | 1.52 × 10−2 | 7.64 × 10−3 | 4.49 | 3.40 × 10−2 | 3.95 |
| FA 18:3 n6 | 2.90 × 10−2 | 6.06 × 10−3 | 3.18 | 4.14 × 10−2 | 2.54 |
| MUFA | 2.91 × 10−2 | 4.79 × 10−3 | 0.27 | 5.00 × 10−2 | 0.32 |
Adjusted p* Values: The value is adjusted with the values of the waist circumference and the HOMA-IR values.