Fig. 4. SARS-CoV-2 response eQTL effects revert to baseline in longitudinal follow-up samples.

(A) Effect sizes for the cell type-specific reQTL gene sets plotted across innate immune cell types in healthy controls, patients, and follow-up samples. All eQTL effect sizes correspond to mash posterior effect sizes. (B) Distribution of the change in eQTL effect sizes between follow-up and patient samples (defined as |follow-up β_eQTL| - |COVID-19 patient β_eQTL|) for response eQTL (n = 370, blue) and shared eQTL (n = 1,653, gray) in CD14⁺ monocytes. Dashed lines represent the mean Δ response magnitude for the respective gene sets.