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. 2024 Nov 25;29(23):5559. doi: 10.3390/molecules29235559

Figure 6.

Figure 6

The quantification of astrocytes and BDNF between the stratum lacunosum moleculare (SLM) and stratum radiatum (SR) and in the CA3 region in the hippocampus of chronic inflammation model mice. (a) The locations of the captured images and quantification in the hippocampus are shown with squares. (b) Representative images of astrocytes, BDNF, and merged, stained with either an anti-GFAP or anti-BDNF antibody in the SLM and SR. Scale bar = 100 μm. (c) Quantification of GFAP-positive signals in the SLM and SR. (d) The quantification of BDNF-positive signals in the SLM and SR. (e) The quantification of GFAP-positive signals in the CA3 region. (f) The quantification of BDNF-positive signals in the CA3 region. Data were analyzed by performing a one-way ANOVA followed by Dunnett’s multiple comparison test. *** p < 0.001 indicates a significant difference between CON and LPS; * p < 0.05, ** p < 0.01 or *** p < 0.001 indicates a significant difference between LPS and HMF-H. Values are presented as the mean ± SEM (n = 3–4 brain sections/mouse in each group).