Table 1.
Clinical characteristics of patients from trial ALL-BFM 2000
| Patients ALL-BFM 2000 (n = 443) | |
| Number of subjects (%) | |
| Gender | |
| Male | 268 (60.5) |
| Female | 175 (39.5) |
| Age at diagnosis (years) | |
| < 1 | - |
| 1-< 6 | 264 (59.6) |
| 6-< 10 | 80 (18.1) |
| ≥ 10 | 99 (22.3) |
| DNA indexa | |
| < 1.16 | 258 (58.2) |
| ≥ 1.16 | 48 (10.8) |
| no result | 137 (30.9) |
| TEL/AML1 pos. | 90 (20.3) |
| neg. | 313 (70.7) |
| unknown | 40 (9.0) |
| BCR/ABL pos. | 9 (2.0) |
| neg. | 412 (93.0) |
| unknown | 22 (5.0) |
| MLL/AF4 pos. | 1 (0.2) |
| neg. | 394 (88.9) |
| unknown | 48 (9.9) |
| Immunophenotype | |
| Precursor B | 344 (77.7) |
| T | 81 (18.3) |
| Bipenotypic | 4 (0.9) |
| Unknown | 14 (3.2) |
aRatio of DNA content of leukemic G0/G1 cells to normal diploid lymphocytes.