Table 1.
Baseline Characteristics | |
---|---|
Gestational age at birth (weeks) | 29.1 (2.8)//30.0 (26.4–31.4) |
Birthweight (g) | 1255 (433)//1337 (839–1588) |
Gender: Male | 20/45 (44%) |
Fetal growth restriction | 4/45 (9%) |
Multiple (twin or triplet) | 15/45 (33%) * |
Postnatal age at blood sampling | |
T1 (days) | 46 (26)//41 (15–110) |
T2 (days) | 150 (52)//150 (69–238) |
Nutritional data | |
Parenteral nutrition | |
Received | 32/45 (71%) |
Days ** | 11.2 (5.6)//10.0 (7.0–14.8) |
Enteral feeding | |
Days at start | 1.9 (1.7)//2.0 (1.0–2.0) |
Days at full feeds | 11.5 (7.2)//10.0 (6.0–15.0) |
Oral folic acid supplement | |
Yes | 5/45 (11.1%) |
Total days where given | 93 (29)//78 (72–100) |
Type of feeding | |
T1 | |
Unfortified breastmilk | 7 (16%) |
Fortified breastmilk | 32 (71%) |
Mixed feeding *** | 6 (13%) |
T2 | |
Breastmilk only | 12 (32%) |
Mixed feeding | 9 (24%) |
Formula feeding | 16 (43%) |
Data are represented by the mean (standard deviation)//median (IQR range) or n (%). T1—time of first blood sample, near discharge. T2—time of second blood sample, on follow-up at 2–3 months’ corrected age. * 2 participants from one set of triplets, 3 from 3 sets of twins in which the other sibling did not participate, and 5 sets of twins. ** Calculated from the group of 32 infants who received PN. *** Includes one infant who switched to formula feeding from recruitment to T1. Among babies receiving mixed feeding, 2/5 had unfortified breastmilk and 3/5 were on fortifier.