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. 2024 Nov 12;16(11):e73562. doi: 10.7759/cureus.73562

Table 1. Demographic data of patients with cystic fibrosis and vitamin E deficiency and those with normal levels.

Data are presented as number (%), mean ± standard deviation, or median (interquartile range).

aFisher’s exact test; bMann-Whitney U test; cStudent t-test; dPearson's chi-square

P-value < 0.05 is considered statistically significant.

Bold values indicate statistical significance.

IQR: interquartile range; SD: standard deviation; BMI: body mass index; ADEK: fat-soluble vitamins A, D, E, and K

Variables Vitamin E Level P-value Total, n = 35 (100)
Low, n = 9 (25.7) Normal, n = 26 (74.3)
Sex                        Male 3 (33.3) 15 (57.7) 0.264a 18 (51.4)
                              Female 6 (66.7) 11 (42.3)   17 (48.6)
Age at presentation (y), median (IQR) 0.4 (0.0-10.3) 0.3 (0.2-0.5) 0.763b 0.3 (0.2-0.5)
Age at time of study (y), mean ± SD 4.5 ± 5.5 7.6 ± 4.2 0.09c (CI: -6.7, 0.5) 6.8 ± 4.7
Age groups (y)     0-4.9 6 (66.7) 7 (26.9) 0.145d 13 (37.1)
                              5-9.9 1 (11.1) 12 (46.2)   13 (37.1)
                              10-14.9 2 (22.2) 6 (23.1)   8 (22.9)
                              15-18 0 (0.0) 1 (3.8)   1 (2.9)
Nationality            Bahraini 8 (88.9) 21 (80.8) 1.000a 29 (82.9)
                              Non-Bahraini 1 (11.1) 5 (19.2)   6 (17.1)
Height at presentation (cm), median (IQR) 76 (67-106) 125 (94-131) 0.681b 117 (98-131)
Weight at presentation (kg), mean ± SD 12.7 ± 9.0 20.2 ± 9.4 0.045c (CI: 0.18, 14.8) 18.2 ± 9.7
BMI (kg/m2), mean ± SD 14.4 ± 2.4 14.2 ± 1.9 0.793c (CI: -1.9, 1.3) 14.3 ± 1.9
Off ADEK duration (mo), median (IQR) 2 (0.5-24) 5.5 (2-12) 0.786b 3 (0.9-12)
Previous gastrointestinal surgery 2 (22.2) 5 (19.2) 1.000a 7 (20)
Number of hospital admissions, median (IQR) 4 (3-6) 3 (2-7) 0.323b 3 (2-7)
Number of pulmonary exacerbations, median (IQR) 4 (2-6) 3 (1-6) 0.305b 3 (1-6)